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Flow Cytometry is an essential resource for investigators performing research in cancer and cancer related areas. With the increasing number of assays being developed which utilize flow cytometry, this resource supports a diverse group of investigators. The Flow Cytometry Core Facility has been used to address questions in cellular immunology, cell biology, chemical carcinogenesis, radiology, human tumor cell cycle kinetics, mechanisms of drug action and differences between patient samples and normal donors.
Our Mission
Supporting clinical trials for immunotherapy of human cancer, for physicians involved in clinical trials for immunotherapy of human cancer, the Beckman Center for Immune Monitoring Core offers several assays to assess patient immune responses. Such assays provide a highly sensitive means of measuring the efficacy of an experimental treatment. It can help establish proof of principle that a treatment works, and suggest changes to adapt a standard treatment protocol to individual patient needs. Besides the Gold Standard of Immune monitoring: the ELISPOT assay for detection of cytokines released by activated T cells, we also perform intracellular cytokine staining and can detect tumor specific T cells by MHC tetramer analysis. Helper and killer T cells can be separated, and proliferative and cytotoxic responses are quantified in radioactive assays. The monitoring protocol of choice is tailor made to fit the needs and the possibilities of each treatment protocol. The core offers freezing and storage capacity for your samples and full analytical support for monitoring assays. It is also possible to send in samples for post-assay analysis using our state-of-the-art ELISPOT reader.
The Immune Monitoring Core at USC/Norris Comprehensive Cancer Center offers advice, technical support and equipment for all your Immune Monitoring needs. Whether you are a physician and you have samples that you would like to test for parameters that match your clinical responses, you are a graduate student looking for equipment to quantify your ELISPOT data or you are writing a research proposal that includes an immune monitoring component, this is the place to be. Browse through our site to find descriptions of available tests, basic pricing and availability information. If you want to discuss your approach, feel free to contact us directly. You'll find our contact information in the menu. When you are ready to send your samples, call us to arrange for transportation.
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All order forms now require you to be logged in before placing orders. Please click here to log in or click here to create a USC Norris website account.
Turnaround time based on Flow Cytometry instrument availability. For availability calendar click here.
Contact us for further information.
USC/Norris Comprehensive Cancer Center
Flow Cytometry Core Facility HMR 704
1441 Eastlake Avenue
Los Angeles, CA 90089
Mabel and Arnold Beckman Center for Immune Monitoring
Harlyne J. Norris Cancer Research Tower, Room 7517
University of Southern California
1450 Biggy Street Los Angeles, CA 90033
Flow Cytometry Core Facility
David Horwitz, MD
Director
Telephone: (323) 442-1949
Fax: (323) 442-2874
Email-dhorwitz@usc.edu
John Dixon Gray, PhD
Core Supervisor 2
Telephone: (323) 442-1948
Fax: (323) 442-2874
Email: jdgray@usc.edu
Hal Soucier
Operator
Telephone: (323) 442-1954
Email: corefacs@ccnt.usc.edu
Mabel and Arnold Beckman Center for Immune Monitoring
W. Martin Kast, PhD
Director
Telephone: (323) 442-3870
Fax: (323) 442-7760
Email: mkast@usc.edu
Diane Da Silva, PhD
Core Manager
Telephone: (323) 442-3869
Fax: (323) 442-7760
Email: ddasilva@usc.edu
Mauri Mackie
Operator
Telephone: (323) 442-3869
Email: CoreIM@ccnt.usc.edu
Flow Cytometry Core Facility
Hal Soucier
Telephone: (323) 442-1954
Email: corefacs@ccnt.usc.edu
Mabel and Arnold Beckman Center for Immune Monitoring
Mauri Mackie
Telephone: (323) 442-3869
Email: CoreIM@ccnt.usc.edu