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The Center for Biomedical Informatics Sciences (CBIS) combines biomedical informatics and biostatistical design under one umbrella to optimize service, training, and methodological developments in relation to study design, information management, and data analysis. CBIS provides researchers with the ability to share data across institutions. We provide services and infrastructure that help to streamline publications, discovery, and query of data. We provide data transfer and management services, along with research support services such as bioinformatics, statistical analysis, and the application and development of novel methods for translational research. CBIS provides web-based solutions to the the Office of Community Engagement to assist in identifying the community’s health-related needs and concerns. The CBIS service-oriented platform provides state-of-the-art Grid Security infrastructure that builds on a variety of security standards to provide authentication and access control for the management and sharing of research information and data.